DMT (N,N-Dimethyltryptamine) is known to be a psychoactive substance derived from the tryptamine family with an identical structure to 5-hydroxytryptamine (serotonin) and melatonin. When taken orally, DMT is mostly thought to be inactive unless at the same time eaten with an MAOI (monoamine oxidase inhibitor). An monoamine oxidase inhibitor prevents the catalyst “monoamine oxidase” from quickly oxidizing the DMT, thereby facilitating a psychedelic experience.
Psychedelic effects reported following ingestion of DMT include: hallucinations, visuals, sensory alterations, and even out-of-body experiences. For this reason, many individuals deliberately ingest DMT for a variety of reasons including: as part of a ceremony or tradition, to explore consciousness/perception, and/or to induce a spiritual/mystical experience. DMT is noted to trigger psychedelic effects via binding to receptors of 5-hydroxytryptamine (serotonin), dopamine, and norepinephrine within your brain.
Though many of us have favorable psychotropic experiences with DMT, some users report less pleasurable psychedelic visits. DMT could provoke the betterment of traumatic recollections, mood swings, depersonalization, or severe drug-induced psychopathy. As a result of these displeasing effects, a user could still wonder however long the DMT will stay in their system after intake.
If you were to require DMT while not a concomitant antidepressant (MAOI), you’d find yourself quickly metabolizing it via MAO “A” enzymes. Erowid reports that the common elimination half-life of DMT is around a quarter-hour (15mins) in humans.
This indicates that fifty percent of exogenously eaten DMT dose can are cleared from the plasma in around quarter-hour (15mins).
Complete plasma clearance of DMT can so take around one hour twenty-three minutes. Assuming that the fifteen-minute half-life applies to you, you may expect to eject the drug absolutely (in the shape of metabolites) inside two (2) hours of your dose. Other factors like the precise DMT you took (source, dosage, etc.) and route of administration could have an effect on plasma clearance. In different words, the drug can linger in your body for up to an hour from when your psychedelic expertise ends.